Gene Regulatory Network Analysis

Problem definition: Analyse the dynamics of Gene Regulatory Networks by inferring these networks from observed behaviours.

With the mapping of the human genome complete, the focus in computational biology has shifted from sequence analysis to the understanding of gene regulation and its inter-relation with the biological system. A gene regulatory network (GRN) is a collection of genes that interact with each other. The inference of gene predictors in the GRN has become an important research area in the genomics and medical disciplines. For instance, the urgent applications to cancer and gene-related diseases calls for the genomics field to significantly improve the algorithms used for accurate inference of the GRN.